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Anorexia Nervosa (AN) is a biologically-based brain disorder, which has the highest death rate of all mental illnesses. No effective treatments exist for adults with severe and enduring AN (5-7+ years). Brain imaging studies at University of California San Diego on AN temperament, cognition and eating show common traits related to neural function. The temperaments are characterized by increased trait anxiety and state anxiety related to food and eating, high incidence of co-morbid anxiety disorders, high punishment sensitivity and low reward reactivity, elevated intolerance of uncertainty and exaggerated harm avoidance (HA). HA is a multifaceted temperament trait that contains elements of anxiety, inhibition and inflexibility.
Neuroscience and Neurobiology | Nutritional and Metabolic Diseases
The Center for Balanced Living, "Family Based Treatment for Adults with Anorexia Nervosa Using Insights from Neurobiology" (2016). Learning Showcase 2016: A Celebration of Discovery, Transformation and Success. 28.